A hand is the epitome of a person, which narrates his life with ups and downs. In the first, a luxurious hand with the status abuses his slaves arrogantly. However, when cholera broke out, he lost his beloved relatives as well as his fortune. After rise and fall, he started thinking about the meaning of life slowly. Lastly, he decided to make contributions to the medical study by his body. The results reflect the influences of environmental pollution on humans. No matter poor or rich, people are all helpless without exception. People are attempting to elaborate the duties and meanings of life.